Analysis of Fusobacterium nucleatum Driven Modulation of c-Myc Pathways in Oral Carcinogenesis

<i>F. nucleatum</i> colonization correlates with increased c-Myc expression in OPMDs and OSCC, supporting its possible role in microbially driven oral carcinogenesis. These findings suggest its potential as a prognostic biomarker and a therapeutic target.

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Publication Details

Journal
F1000Research
Published
2026-02-03
DOI
https://doi.org/10.12688/f1000research.177011.1
Primary Topic
Oral Health Pathology and Treatment
Type
article
Field-Weighted Citation Impact
0.00

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article

Analysis of Fusobacterium nucleatum Driven Modulation of c-Myc Pathways in Oral Carcinogenesis

Atrey J. Pai Khot, Anshi Jain, Shefali Yadav, Charu Priya et al.
F1000Research
Oral Health Pathology and Treatment
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Analysis of Fusobacterium nucleatum Driven Modulation of c-Myc Pathways in Oral Carcinogenesis

Atrey J. Pai Khot, Anshi Jain, Shefali Yadav, Charu Priya, Sultan A. Almalki, Inderjit M. Gowdar, Nikita Gulati, Mahima Jain, Devi Charan Shetty
article en

Abstract

<i>F. nucleatum</i> colonization correlates with increased c-Myc expression in OPMDs and OSCC, supporting its possible role in microbially driven oral carcinogenesis. These findings suggest its potential as a prognostic biomarker and a therapeutic target.

F1000ResearchVol. 15
Prince Sattam Bin Abdulaziz University (SA), Goa Dental College and Hospital (IN), Kothiwal Dental College and Research Centre (IN)
Prince Sattam bin Abdulaziz University
Good health and well-being
Openalex Percentile: Top 68%
Oral Health Pathology and Treatment
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