A Rare Linitis Plastica Manifestation of Esophageal Squamous Cell Carcinoma With Diffuse Gastric Metastasis Revealed by 18F-FDG PET/CT

Diffuse gastric metastasis of esophageal squamous cell carcinoma (SCC) manifested as linitis plastica is extremely rare. A 49-year-old man complained of postprandial vomiting and epigastric colicky pain, and biopsy indicated mucosal inflammation. 18F-FDG PET/CT revealed diffuse wall thickening of mid-to-lower esophagus and diffuse gastric wall thickening accompanied by mediastinal lymph node, perigastric, and peripancreatic lesions with intense FDG accumulation. Malignancy of mid-to-lower esophagus and linitis plastica accompanied by lymph node, perigastric, and peripancreatic metastases was suspected. Biopsies of multiple sites of esophagus and stomach confirmed SCC. 18F-FDG PET/CT is instrumental for evaluating rare metastasis of esophageal SCC and guiding biopsy.

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Publication Details

Journal
Clinical Nuclear Medicine
Published
2026-02-03
DOI
https://doi.org/10.1097/rlu.0000000000006275
Primary Topic
Metastasis and carcinoma case studies
Type
article
Field-Weighted Citation Impact
0.00
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article

A Rare Linitis Plastica Manifestation of Esophageal Squamous Cell Carcinoma With Diffuse Gastric Metastasis Revealed by 18F-FDG PET/CT

Bulin Du, Yaming Li, Yan Cui, Xuena Li et al.
Clinical Nuclear Medicine
Metastasis and carcinoma case studies
article

A Rare Linitis Plastica Manifestation of Esophageal Squamous Cell Carcinoma With Diffuse Gastric Metastasis Revealed by 18F-FDG PET/CT

Bulin Du, Yaming Li, Yan Cui, Xuena Li, Yingqi Wang
article en

Abstract

Diffuse gastric metastasis of esophageal squamous cell carcinoma (SCC) manifested as linitis plastica is extremely rare. A 49-year-old man complained of postprandial vomiting and epigastric colicky pain, and biopsy indicated mucosal inflammation. 18F-FDG PET/CT revealed diffuse wall thickening of mid-to-lower esophagus and diffuse gastric wall thickening accompanied by mediastinal lymph node, perigastric, and peripancreatic lesions with intense FDG accumulation. Malignancy of mid-to-lower esophagus and linitis plastica accompanied by lymph node, perigastric, and peripancreatic metastases was suspected. Biopsies of multiple sites of esophagus and stomach confirmed SCC. 18F-FDG PET/CT is instrumental for evaluating rare metastasis of esophageal SCC and guiding biopsy.

Clinical Nuclear MedicineVol. 51(3)
National Health Insurance Fund (RS), First Hospital of China Medical University (CN), China Medical University (CN)
Good health and well-being
Openalex Percentile: Top 70%
Metastasis and carcinoma case studies
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