Hepatic Vascular Shunts Mimicking Malignant Lesions on 18F-FDG PET/CT Imaging: Interpretation Pitfall in the Background of Cirrhotic Liver

A 44-year-old female presented with recent history of ischemic strokes and hypercoagulability and chronic alcoholic cirrhosis. <sup>18</sup>F-fluorodeoxyglucose (FDG) positron emission tomography (PET)/computed tomography was performed during the workup for vasculitis. PET features of vasculitis were not identified, but liver showed multiple hepatic FDG avid foci, concerning for malignant or metastatic disease in the background of cirrhosis of liver. To characterize these lesions, liver magnetic resonance imaging was subsequently performed which revealed hepatic vascular shunts corresponding to the sites of the FDG avid foci. This case highlights potential interpretation n pitfall arising due to FDG avidity in the vascular shunts resembling malignant or metastatic lesions.

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Publication Details

Journal
Molecular Imaging and Radionuclide Therapy
Published
2026-02-03
DOI
https://doi.org/10.4274/mirt.galenos.2025.45712
Primary Topic
Liver Disease and Transplantation
Type
article
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article

Hepatic Vascular Shunts Mimicking Malignant Lesions on 18F-FDG PET/CT Imaging: Interpretation Pitfall in the Background of Cirrhotic Liver

Sanchay Jain, Parren McNeely, Assim Saad Eddin, Michael Graham et al.
Molecular Imaging and Radionuclide Therapy
Liver Disease and Transplantation
article

Hepatic Vascular Shunts Mimicking Malignant Lesions on 18F-FDG PET/CT Imaging: Interpretation Pitfall in the Background of Cirrhotic Liver

Sanchay Jain, Parren McNeely, Assim Saad Eddin, Michael Graham, Ahmad Shariftabrizi
article en

Abstract

A 44-year-old female presented with recent history of ischemic strokes and hypercoagulability and chronic alcoholic cirrhosis. <sup>18</sup>F-fluorodeoxyglucose (FDG) positron emission tomography (PET)/computed tomography was performed during the workup for vasculitis. PET features of vasculitis were not identified, but liver showed multiple hepatic FDG avid foci, concerning for malignant or metastatic disease in the background of cirrhosis of liver. To characterize these lesions, liver magnetic resonance imaging was subsequently performed which revealed hepatic vascular shunts corresponding to the sites of the FDG avid foci. This case highlights potential interpretation n pitfall arising due to FDG avidity in the vascular shunts resembling malignant or metastatic lesions.

Molecular Imaging and Radionuclide TherapyVol. 35(1)
University of Iowa Health Care (US)
Good health and well-being
Openalex Percentile: Top 67%
Liver Disease and Transplantation
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Hepatic Vascular Shunts Mimicking Malignant Lesions on 18F-FDG PET/CT Imaging: Interpretation Pitfall in the Background of Cirrhotic Liver — Sanchay Jain, Parren McNeely, et al. · Molecular Imaging and Radionuclide Therapy (2026) | TGRS Research Map | TGRS