Increased Incidence of De Novo Malignancies Compared With Malignancy Recurrences in Survivors of Cancer Undergoing Heart Transplantation
CS are 4 times more likely to have de novo malignancies unrelated to their primary malignancy rather than a recurrence. Despite the high rate of SPC, survival in this cohort was comparable to contemporary survival in HT patients. Further studies are required to understand optimal prevention and screening for SPC in CS undergoing HT beyond recommendations in the general population.
Authors
- Stephanie Golob (ORCID: https://orcid.org/0000-0002-4600-8871)
- Sarah Godfrey (ORCID: https://orcid.org/0000-0003-2896-2124)
- Kevin J. Clerkin (ORCID: https://orcid.org/0000-0001-8351-9219)
- J. Raikhelkar
- F. Z. Ab. Latif
- Yûji Kaku
- Ersilia M. DeFilippis (ORCID: https://orcid.org/0000-0002-0493-1326)
- Daniel Oren (ORCID: https://orcid.org/0000-0002-2447-3713)
- Matthew Regan
- Jaya Batra (ORCID: https://orcid.org/0000-0002-5235-0163)
- Nir Uriel (ORCID: https://orcid.org/0000-0003-2301-3587)
- Justin Fried
- Yoshifumi Naka
- Gabriel Sayer
- Melana Yuzefpolskaya
- Veli Topkara
- Paolo Colombo
- Koji Takeda
Institutions
- University of Wisconsin–Madison (US)
- Columbia University Irving Medical Center (US)
- Cooper University Health Care (US)
- Southwestern Medical Center (US)
- New York University (US)
- The University of Texas Southwestern Medical Center (US)
Publication Details
- Journal
- Journal of the American Heart Association
- Published
- 2026-02-03
- DOI
- https://doi.org/10.1161/jaha.125.042779
- Primary Topic
- Multiple and Secondary Primary Cancers
- Type
- article
- Field-Weighted Citation Impact
- 0.00