Characterization of a conjugative IncFII/IncR plasmid harboring blaKPC-2 in a clinical ST91 Citrobacter freundii isolate
To our knowledge, this is the first characterization of an IncFII(pBK30683)/IncR plasmid carrying bla<sub>KPC-2</sub> in a clinical C. freundii ST91 isolate. The findings highlight plasmid lineages as drivers of carbapenem resistance dissemination and underscore the need for plasmid-focused genomic surveillance, particularly for monitoring transferable resistance vehicles across clinically relevant hosts.
Authors
- Haishan Gao (ORCID: https://orcid.org/0000-0002-4954-8793)
- Duochun Wang (ORCID: https://orcid.org/0000-0003-2372-1532)
- Xiao Liu
- Bike Zhang
- Guodong Yan
- Zhiwen Sun
- Zhen Liu
Institutions
- Chinese Academy of Sciences (CN)
- Gansu University of Traditional Chinese Medicine (CN)
- Institute of Microbiology (CN)
- National Institute for Communicable Disease Control and Prevention (CN)
Publication Details
- Journal
- BMC Microbiology
- Published
- 2026-02-04
- DOI
- https://doi.org/10.1186/s12866-026-04795-1
- Primary Topic
- Antibiotic Resistance in Bacteria
- Type
- article
- Field-Weighted Citation Impact
- 0.00