Cellular uptake of extracellular dsRNA is tissue-dependent in insects
Taken together, dsRNA enters the cells of different tissue types through diverse pathways. This systematic and comprehensive study not only advances our understanding of the cellular uptake of extracellular dsRNA and the resultant differential sensitivity to RNAi in insects, but also facilitates the ongoing integration of this species-specific biotechnology into sustainable integrated pest management practices.
Authors
- Hans Merzendorfer (ORCID: https://orcid.org/0000-0003-4830-8162)
- xiaojian liu (ORCID: https://orcid.org/0009-0009-2903-0346)
- Kun Yan Zhu (ORCID: https://orcid.org/0000-0001-9372-8030)
- Austin Merchant
- Mureed Abbas
- Xuekai Shi
- Xuguo Zhou
- Jianzhen Zhang
- Yaoming Liu
- Zhangwu Zhao
Institutions
- University of Kentucky (US)
- University of Illinois Urbana-Champaign (US)
- Taiyuan Normal University (CN)
- Shanxi University (CN)
- Kansas State University (US)
- University of Siegen (DE)
Publication Details
- Journal
- BMC Biology
- Published
- 2026-02-03
- DOI
- https://doi.org/10.1186/s12915-026-02526-6
- Primary Topic
- Insect Resistance and Genetics
- Type
- article
- Field-Weighted Citation Impact
- 0.00