Blood pressure thresholds for the administration of balanced crystalloids and the effect on intra-operative hypotension

Using modern causal inference methods, we demonstrated the clinical utility of idealised DTRs to study the impact of time-dependent haemodynamic management on the incidence of intra-operative hypotension in idealised settings. Future studies are required to investigate more complex DTRs mirroring clinical practice and to assess the robustness of the findings with respect to the different surgical populations.