Adaptation of MALDI-TOF MS Technique for Tracking Changes in the Urinary Microbiome During and After Radiotherapy for Prostate Cancer
RT triggers a dynamic response in the urinary microbiome, with an initial decline in diversity followed by progressive recolonization. Glucose levels in urine and blood significantly affect microbial composition, suggesting that metabolic factors modulate RT-related microbiome shifts. These findings highlight the interplay between RT, host metabolism, and urinary microbiota, supporting the potential value of glucose monitoring to maintain microbial balance after RT.
Authors
- Paweł Pomastowski (ORCID: https://orcid.org/0000-0002-1594-0623)
- Adrian Arendowski (ORCID: https://orcid.org/0000-0002-8496-6800)
- Monika Pietrowska (ORCID: https://orcid.org/0000-0001-9317-7822)
- Wioletta Miśta
- Ewa Telka (ORCID: https://orcid.org/0000-0003-2378-412X)
- Ewelina Sibińska (ORCID: https://orcid.org/0000-0002-5848-0102)
- Piotr Fijałkowski (ORCID: https://orcid.org/0009-0006-8166-7617)
- Kinga Karoń
- Małgorzata Rabsztyn
- Fernanda Ferreira da Silva Souza Monedeiro
- Michał Złoch
- Anna Jędrzejewska
- Jolanta Mrochem-Kwarciak
- Dorota Gabryś
Institutions
- Rzeszów University of Technology (PL)
- Nicolaus Copernicus University (PL)
- National Institute of Oncology (HU)
- The Maria Sklodowska-Curie National Research Institute of Oncology (PL)
Publication Details
- Journal
- Cancer Management and Research
- Published
- 2026-02-01
- DOI
- https://doi.org/10.2147/cmar.s573379
- Primary Topic
- Bacterial Identification and Susceptibility Testing
- Type
- article
- Field-Weighted Citation Impact
- 0.00