Groove area involvement predicts post-ERCP pancreatitis after 8-mm fully-covered metal stent placement in resectable pancreatic cancer

Groove-area tumor extension is an independent imaging-detectable PEP risk factor. Even after baseline difference adjustment, 8-mm FCSEMS placement was associated with a higher pancreatitis risk than PS placement. Pre-procedural groove involvement identification may guide stent selection and support selective prophylactic pancreatic stenting. However, further confirmation through larger prospective studies is required.