Limited genome evolution of <i>Cryptococcus neoformans</i> following an accidental infection in the research laboratory

In a span of 5 years, four laboratory researchers from two research groups at the same institution sustained accidental exposures to <i>C. neoformans</i>, and all were successfully treated. These cases reinforce and update the recommendations for initiating antifungal therapy immediately after laboratory accidents involving <i>C. neoformans</i>.

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Publication Details

Journal
ASM Case Reports
Published
2026-02-03
DOI
https://doi.org/10.1128/asmcr.00209-25
Primary Topic
Fungal Infections and Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Limited genome evolution of Cryptococcus neoformans following an accidental infection in the research laboratory

Daniel F. Q. Smith, Yunfan Fan, Sean X. Zhang, Madhura Kulkarni et al.
ASM Case Reports
Fungal Infections and Studies
article

Limited genome evolution of Cryptococcus neoformans following an accidental infection in the research laboratory

Daniel F. Q. Smith, Yunfan Fan, Sean X. Zhang, Madhura Kulkarni, Arturo Casadevall, David J. Sullivan, J. Marie Hardwick
article en

Abstract

In a span of 5 years, four laboratory researchers from two research groups at the same institution sustained accidental exposures to <i>C. neoformans</i>, and all were successfully treated. These cases reinforce and update the recommendations for initiating antifungal therapy immediately after laboratory accidents involving <i>C. neoformans</i>.

ASM Case ReportsVol. 2(2)
Johns Hopkins University (US), Johns Hopkins Medicine (US), Johns Hopkins Hospital (US), Sidney Kimmel Comprehensive Cancer Center (US)
Openalex Percentile: Top 67%
Fungal Infections and Studies
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Limited genome evolution of <i>Cryptococcus neoformans</i> following an accidental infection in the research laboratory — Daniel F. Q. Smith, Yunfan Fan, et al. · ASM Case Reports (2026) | TGRS Research Map | TGRS