Nonlinear association between hematocrit and 3-month outcome after acute ischemic stroke: identification of threshold effects in males

This study revealed a nonlinear, sex-specific relationship between HCT and 3-month outcome in AIS patients. In male patients, HCT levels below the threshold were inversely associated with adverse outcome, while no significant association was observed in female patients.

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Publication Details

Journal
Frontiers in Medicine
Published
2026-02-04
DOI
https://doi.org/10.3389/fmed.2026.1721251
Primary Topic
Acute Ischemic Stroke Management
Type
article
Field-Weighted Citation Impact
0.00

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article

Nonlinear association between hematocrit and 3-month outcome after acute ischemic stroke: identification of threshold effects in males

Xiaomin Liang, Zemao Xing, Qian Wang, Shuiqing Gui
Frontiers in Medicine
Acute Ischemic Stroke Management
article

Nonlinear association between hematocrit and 3-month outcome after acute ischemic stroke: identification of threshold effects in males

Xiaomin Liang, Zemao Xing, Qian Wang, Shuiqing Gui
article en

Abstract

This study revealed a nonlinear, sex-specific relationship between HCT and 3-month outcome in AIS patients. In male patients, HCT levels below the threshold were inversely associated with adverse outcome, while no significant association was observed in female patients.

Frontiers in MedicineVol. 13
Chinese University of Hong Kong, Shenzhen (CN), Shenzhen Second People's Hospital (CN)
Sanming Project of Medicine in Shenzhen
Good health and well-being
Openalex Percentile: Top 67%
Acute Ischemic Stroke Management
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