Impact of female underrepresentation in trials investigating long-term pharmacologic therapy after acute coronary syndrome: a meta-analysis and meta-regression
In RCTs of long-term pharmacological therapy after ACS, treatment efficacy was comparable between sexes, irrespective of sex distribution. These findings support current guidelines recommending equivalent long-term pharmacological strategies for secondary prevention in both sexes.
Authors
- Astrid Schut (ORCID: https://orcid.org/0000-0001-9397-7109)
- H M R Den Ruijter
- Lotte Paulis
- Marte F van der Bijl
- Iris C D Westendorp
- Eric Boersma
- Jeanine E Roeters van Lennep
Institutions
- Utrecht University (NL)
- Erasmus MC (NL)
- University Medical Center Utrecht (NL)
- Red Cross Hospital (GR)
- Amsterdam Neuroscience (NL)
- Amsterdam University Medical Centers (NL)
- Dutch College of General Practitioners (NL)
- Amsterdam UMC Location Vrije Universiteit Amsterdam (NL)
Publication Details
- Journal
- European Heart Journal Acute Cardiovascular Care
- Published
- 2026-02-03
- DOI
- https://doi.org/10.1093/ehjacc/zuag020
- Primary Topic
- Sex and Gender in Healthcare
- Type
- article
- Field-Weighted Citation Impact
- 0.00