Nutrition in early life interacts with genetic risk to influence preadult behaviour in the Raine Study

Nutrition in early life and psychiatric genetic risk may interact to determine lasting child behaviour. Contrary to our hypothesis, we find dietary benefits in individuals with lower ADHD PGS, necessitating replication. We also highlight the possibility of including genetics in early nutrition intervention trials for causal inference.

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Publication Details

Journal
Communications Medicine
Published
2026-02-03
DOI
https://doi.org/10.1038/s43856-025-01339-y
Primary Topic
Maternal Mental Health During Pregnancy and Postpartum
Type
article
Field-Weighted Citation Impact
0.00

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article

Nutrition in early life interacts with genetic risk to influence preadult behaviour in the Raine Study

Carol A. Wang, Jonathan J. Hirst, Lars Meinertz Byg, Craig E. Pennell et al.
Communications Medicine
Maternal Mental Health During Pregnancy and Postpartum
article

Nutrition in early life interacts with genetic risk to influence preadult behaviour in the Raine Study

Carol A. Wang, Jonathan J. Hirst, Lars Meinertz Byg, Craig E. Pennell, Wendy H. Oddy, John Attia, Andrew J. O. Whitehouse
article en

Abstract

Nutrition in early life and psychiatric genetic risk may interact to determine lasting child behaviour. Contrary to our hypothesis, we find dietary benefits in individuals with lower ADHD PGS, necessitating replication. We also highlight the possibility of including genetics in early nutrition intervention trials for causal inference.

Communications MedicineVol. 6(1)
University of Tasmania (AU), The Kids Research Institute Australia (AU), John Hunter Hospital (AU), Hunter Medical Research Institute (AU), University of Newcastle Australia (AU)
University of Notre Dame, Australian Government, Raine Medical Research Foundation, Women and Infants Research Foundation, Curtin University of Technology, Edith Cowan University, Murdoch University, University of Notre Dame Australia, Government of Western Australia, Canadian Institutes of Health Research, National Health and Medical Research Council
Zero hunger
Openalex Percentile: Top 70%
Maternal Mental Health During Pregnancy and Postpartum
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Nutrition in early life interacts with genetic risk to influence preadult behaviour in the Raine Study — Carol A. Wang, Jonathan J. Hirst, et al. · Communications Medicine (2026) | TGRS Research Map | TGRS