ALBI and Child-Pugh Score in Predicting Mortality in Chronic Liver Disease Patients Secondary to Alcohol: A Retrospective Comparative Study

The severity of liver dysfunction in chronic liver disease (CLD) is often estimated with Child-Pugh(CTP) classification or model for end‐stage liver disease (MELD) score. The albumin-to-bilirubin (ALBI) score is a newmodel for assessing the severity of liver dysfunction, which is simple and more objective. In the present study, we aimed toretrospectively compare the performance of ALBI score with Child-Pugh score for predicting the mortality in patients withCLD. Material and methods: Data of patients with CLD, irrespective of etiology, were retrospectively reviewed. Child-Pughscore and ALBI score were calculated for the patients and results from receiver operating characteristic (ROC) curves wereanalyzed. Results: The study was conducted on 299 patients of CLD; age distribution was between 20 and 85 years withmean age of patients being 45.7 ± 10.94 years, sex ratio male: female 265:34 with mortality rate of 19.73%. The area underthe curve (AUC) of ROC of ALBI and Child-Pugh were 0.586 and 0.549, respectively. Conclusion: Ability of ALBI score forpredicting mortality was comparable with that of Child-Pugh score but Child-Pugh score of >10 had better performance ofpredicting mortality as compared to ALBI score.

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Published
2026-02-03
DOI
https://doi.org/10.59793/zpd3by25
Primary Topic
Alcohol Consumption and Health Effects
Type
article
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article

ALBI and Child-Pugh Score in Predicting Mortality in Chronic Liver Disease Patients Secondary to Alcohol: A Retrospective Comparative Study

B. S. Nagaraja, Sanjeet SB, Madhumathi R.
Alcohol Consumption and Health Effects
article

ALBI and Child-Pugh Score in Predicting Mortality in Chronic Liver Disease Patients Secondary to Alcohol: A Retrospective Comparative Study

B. S. Nagaraja, Sanjeet SB, Madhumathi R.
article en

Abstract

The severity of liver dysfunction in chronic liver disease (CLD) is often estimated with Child-Pugh(CTP) classification or model for end‐stage liver disease (MELD) score. The albumin-to-bilirubin (ALBI) score is a newmodel for assessing the severity of liver dysfunction, which is simple and more objective. In the present study, we aimed toretrospectively compare the performance of ALBI score with Child-Pugh score for predicting the mortality in patients withCLD. Material and methods: Data of patients with CLD, irrespective of etiology, were retrospectively reviewed. Child-Pughscore and ALBI score were calculated for the patients and results from receiver operating characteristic (ROC) curves wereanalyzed. Results: The study was conducted on 299 patients of CLD; age distribution was between 20 and 85 years withmean age of patients being 45.7 ± 10.94 years, sex ratio male: female 265:34 with mortality rate of 19.73%. The area underthe curve (AUC) of ROC of ALBI and Child-Pugh were 0.586 and 0.549, respectively. Conclusion: Ability of ALBI score forpredicting mortality was comparable with that of Child-Pugh score but Child-Pugh score of >10 had better performance ofpredicting mortality as compared to ALBI score.

Institute for Postgraduate Medical Education (CZ), Marymount University (US)
Good health and well-being
Openalex Percentile: Top 70%
Alcohol Consumption and Health Effects
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