Computational physiological modeling for lung-specific ventilation and perfusion management in ex vivo lung perfusion

This CPM enhances understanding of <i>ex vivo</i> lung physiology, which may lead to less injurious EVLP management and support safe, extended-duration EVLP.

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Publication Details

Journal
Frontiers in Physiology
Published
2026-02-03
DOI
https://doi.org/10.3389/fphys.2025.1724724
Primary Topic
Transplantation: Methods and Outcomes
Type
article
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article

Computational physiological modeling for lung-specific ventilation and perfusion management in ex vivo lung perfusion

Lex M. van Loon, Frans H C De Jongh, Eline Oppersma, Sue A. Braithwaite et al.
Frontiers in Physiology
Transplantation: Methods and Outcomes
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Computational physiological modeling for lung-specific ventilation and perfusion management in ex vivo lung perfusion

Lex M. van Loon, Frans H C De Jongh, Eline Oppersma, Sue A. Braithwaite, Dirk Donker, Daan Imholz, Linda M. de Heer, Paul Blankman, Bart Luijk, Wolfgang F. F. A. Buhre
article en

Abstract

This CPM enhances understanding of <i>ex vivo</i> lung physiology, which may lead to less injurious EVLP management and support safe, extended-duration EVLP.

Frontiers in PhysiologyVol. 16
Medisch Spectrum Twente (NL), University Medical Center Utrecht (NL), Max Planck University of Twente Center for Complex Fluid Dynamics (NL), University of Twente (NL)
Good health and well-being
Openalex Percentile: Top 68%
Transplantation: Methods and Outcomes
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