Safety and tolerability of avacincaptad pegol in combination with ranibizumab in treatment-naïve patients with neovascular age-related macular degeneration: results from a phase 1 and phase 2a study
Coadministration of ACP and ranibizumab in treatment-naïve patients with nAMD was well tolerated across different dosing regimens with no new safety issues based on results from two independent studies.
Authors
- Dhaval Desai
- Liansheng Zhu
- Justin Tang (ORCID: https://orcid.org/0000-0001-6658-2558)
- Julie Clark
- Sunil S Patel
- Anat Loewenstein
- David S Boyer
Institutions
- Tel Aviv University (IL)
- Tel Aviv Sourasky Medical Center (IL)
- Retina Vitreous Associates Medical Group (US)
- West Texas Retina Consultants (US)
- Academic College of Tel Aviv-Yafo (IL)
- Astellas Pharma (United States) (US)
Publication Details
- Journal
- BMJ Open Ophthalmology
- Published
- 2026-02-03
- DOI
- https://doi.org/10.1136/bmjophth-2025-002232
- Primary Topic
- Retinal Diseases and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Astellas Pharma