Utility of inhaled β2-agonists in reducing serum potassium levels in adult patients with hyperkalemia: A scoping review

Inhaled β2-agonists, particularly nebulized salbutamol, represent an effective and safe therapeutic option for the acute reduction of serum potassium in adults with hyperkalemia. Their rapid onset of action and applicability across various patient profiles make them a valuable tool in emergency settings, especially where immediate access to advanced therapies such as dialysis is limited. Further research is warranted to evaluate long-term outcomes, safety in patients with cardiovascular comorbidities, and optimal dosing strategies.

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Publication Details

Journal
PLoS ONE
Published
2026-02-03
DOI
https://doi.org/10.1371/journal.pone.0342309
Primary Topic
Potassium and Related Disorders
Type
article
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article

Utility of inhaled β2-agonists in reducing serum potassium levels in adult patients with hyperkalemia: A scoping review

Leonardo Arzayus-Patiño, Vicente Benavides-Cordoba, Karen A. Rodríguez-Angulo, Michelle A. Sánchez-Caicedo et al.
PLoS ONE
Potassium and Related Disorders
article

Utility of inhaled β2-agonists in reducing serum potassium levels in adult patients with hyperkalemia: A scoping review

Leonardo Arzayus-Patiño, Vicente Benavides-Cordoba, Karen A. Rodríguez-Angulo, Michelle A. Sánchez-Caicedo, Ashley Y. Hinojosa-Angulo
article en

Abstract

Inhaled β2-agonists, particularly nebulized salbutamol, represent an effective and safe therapeutic option for the acute reduction of serum potassium in adults with hyperkalemia. Their rapid onset of action and applicability across various patient profiles make them a valuable tool in emergency settings, especially where immediate access to advanced therapies such as dialysis is limited. Further research is warranted to evaluate long-term outcomes, safety in patients with cardiovascular comorbidities, and optimal dosing strategies.

PLoS ONEVol. 21(2)
Universidad Santiago de Cali (CO), Universidad del Valle (CO)
Openalex Percentile: Top 70%
Potassium and Related Disorders
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