Rectal delivered nanocomposite suppository against radiation-induced proctitis
These findings indicate that an EGCG-Zn-based thermosensitive rectal suppository is a safe and effective localized strategy for alleviating radiation-induced proctitis, with potential translational value for the management of radiation-associated rectal injury.
Authors
- Ji Zhu
- Dongxiao Zhang
- Jixu Lu
- Yanlong Liu
Institutions
- Harbin Medical University (CN)
- Affiliated Hospital of Southwest Medical University (CN)
- Zhejiang Party School (CN)
- Zhejiang Cancer Hospital (CN)
- Third Affiliated Hospital of Harbin Medical University (CN)
- Hangzhou Academy of Agricultural Sciences (CN)
Publication Details
- Journal
- Journal of Nanobiotechnology
- Published
- 2026-02-03
- DOI
- https://doi.org/10.1186/s12951-026-04057-2
- Primary Topic
- Effects of Radiation Exposure
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- National Health Commission of the People's Republic of China
- Natural Science Foundation of Zhejiang Province