Iron deficiency definitions and their clinical and prognostic associations across the spectrum of left ventricular ejection fraction in heart failure

ID is common and clinically relevant across the HF spectrum, irrespective of definition, and is associated with impaired quality of life and adverse outcomes in patients with LVEF <50%. In HFpEF, however, the prognostic impact of ID appears less pronounced and may depend on the definition applied, highlighting the need for refined diagnostic criteria in this group.

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Publication Details

Journal
European Journal of Heart Failure
Published
2026-01-29
DOI
https://doi.org/10.1093/ejhf/xuag031
Primary Topic
Erythropoietin and Anemia Treatment
Type
article
Field-Weighted Citation Impact
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article

Iron deficiency definitions and their clinical and prognostic associations across the spectrum of left ventricular ejection fraction in heart failure

Nils Bömer, Niels Grote Beverborg, P. H. Van Der Meer, A W Voors et al.
European Journal of Heart Failure
Erythropoietin and Anemia Treatment
article

Iron deficiency definitions and their clinical and prognostic associations across the spectrum of left ventricular ejection fraction in heart failure

Nils Bömer, Niels Grote Beverborg, P. H. Van Der Meer, A W Voors, Ridha I S Alnuwaysir, Stefan D Anker, Dirk J van Veldhuisen
article en

Abstract

ID is common and clinically relevant across the HF spectrum, irrespective of definition, and is associated with impaired quality of life and adverse outcomes in patients with LVEF <50%. In HFpEF, however, the prognostic impact of ID appears less pronounced and may depend on the definition applied, highlighting the need for refined diagnostic criteria in this group.

European Journal of Heart Failure
University Medical Center Groningen (NL), German Centre for Cardiovascular Research (DE), Charité - Universitätsmedizin Berlin (DE)
Openalex Percentile: Top 70%
Erythropoietin and Anemia Treatment
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Iron deficiency definitions and their clinical and prognostic associations across the spectrum of left ventricular ejection fraction in heart failure — Nils Bömer, Niels Grote Beverborg, et al. · European Journal of Heart Failure (2026) | TGRS Research Map | TGRS