Surgical and survival outcomes of neoadjuvant IMRT-based chemoradiotherapy versus upfront surgery in borderline resectable pancreatic cancer: a retrospective cohort study
Neoadjuvant chemoradiotherapy with IMRT plus gemcitabine and nab-paclitaxel was associated with improved surgical and survival outcomes in patients with BRPC compared to upfront surgery. These findings support the integration of modern chemoradiotherapy into the neoadjuvant treatment paradigm for BRPC and warrant prospective validation.
Authors
- Wentao Cai
- Hui Yang
- Xinru Huang
Institutions
- Wenzhou Medical University (CN)
- First Affiliated Hospital of Wenzhou Medical University (CN)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2026-02-03
- DOI
- https://doi.org/10.3389/fonc.2026.1744117
- Primary Topic
- Pancreatic and Hepatic Oncology Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00