Symptom burden in dialysis patients: determinants and impact on mortality

In the large dataset of the Hemodialysis (HEMO) trial, we found that, among the analyzed variables, those related to eating habits and previous comorbidities were the most closely associated with the symptoms score, both at baseline and during follow-up. Although symptoms were associated with severe clinical outcomes, their prognostic power was limited. However, considering symptom burden in dialysis patients, strict monitoring of eating habits may help improve quality of life in these patients.

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Publication Details

Journal
Journal of Nephrology
Published
2026-02-03
DOI
https://doi.org/10.1093/joneph/aajaf013
Primary Topic
Dialysis and Renal Disease Management
Type
article
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Symptom burden in dialysis patients: determinants and impact on mortality

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Journal of Nephrology
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Symptom burden in dialysis patients: determinants and impact on mortality

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article en

Abstract

In the large dataset of the Hemodialysis (HEMO) trial, we found that, among the analyzed variables, those related to eating habits and previous comorbidities were the most closely associated with the symptoms score, both at baseline and during follow-up. Although symptoms were associated with severe clinical outcomes, their prognostic power was limited. However, considering symptom burden in dialysis patients, strict monitoring of eating habits may help improve quality of life in these patients.

Journal of Nephrology
University of Messina (IT), Università degli Studi di Enna Kore (IT), Azienda ospedaliera "Bianchi-Melacrino-Morelli" (IT), Intelligent Systems Research (United States) (US), Istituto di Fisiologia Clinica (IT), University of Palermo (AR), Campus Bio Medico University Hospital (IT), University of Palermo (IT)
Reduced inequalities
Openalex Percentile: Top 72%
Dialysis and Renal Disease Management
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