BDNF Val66Met Variant as a Genetic Risk Factor for Major Depressive Disorder in Saudis
The BDNF Val66Met polymorphism is associated with MDD susceptibility in Saudis. The Met (A) allele, particularly in homozygosity, confers increased risk, while the Val/Val genotype appears protective, supporting population-specific genetic contributions to depression.
Authors
- Amina M. Bagher (ORCID: https://orcid.org/0000-0002-1850-5686)
- Lenah S. Binmahfouz (ORCID: https://orcid.org/0000-0002-5142-0588)
- Basma G. Eid (ORCID: https://orcid.org/0000-0002-8244-1242)
- Yasmeen Qutub
- Muteb Farhan Saad Alkhaldi
- Alzahraa A. Alzahrani
- Sara A. Albeladi
Institutions
- King Abdulaziz University (SA)
- Saad Specialist Hospital (SA)
Publication Details
- Journal
- Genetic Testing and Molecular Biomarkers
- Published
- 2026-02-01
- DOI
- https://doi.org/10.1177/19450265261419292
- Primary Topic
- Nerve injury and regeneration
- Type
- article
- Field-Weighted Citation Impact
- 0.00