Development of CQDs/WS2 as sensor for the detection of doxycycline and metronidazole
Abstract The antibiotics doxycycline and metronidazole play a vital role in the treatment of infections and diseases. To identify and quantify these two important antibiotics in biological samples, fluorescence spectroscopy was employed. Carbon quantum dots synthesized via a hydrothermal method using yeast, tungsten, and sulfur were used as sensitive probes for the detection and measurement of doxycycline and metronidazole. The synthesized quantum dots were characterized using SEM, EDX, and IR techniques. The results demonstrated that fluorescence spectroscopy can be used as a sensitive and accurate method for the identification and quantification of doxycycline and metronidazole in biological samples. This approach can contribute to the improvement of infection treatment and the maintenance of human health. Compared to other spectroscopic techniques, fluorescence spectroscopy offers advantages such as high speed, low cost, high accuracy, and high sensitivity, as well as the ability to reuse samples. In conclusion, the use of fluorescence spectroscopy with carbon quantum dots as a probe for the identification and quantification of doxycycline and metronidazole in biological samples is an effective and efficient method that can play a significant role in the treatment of infections and the preservation of human health.
Authors
- Bahareh Rahimian Zarif (ORCID: https://orcid.org/0000-0003-2869-7244)
- Shima Kordbahmani
Institutions
- Islamic Azad University, Tehran (IR)
- Islamic Azad University Sanandaj Branch (IR)
Publication Details
- Journal
- Journal of Analytical Science & Technology
- Published
- 2026-02-03
- DOI
- https://doi.org/10.1186/s40543-025-00523-y
- Primary Topic
- Carbon and Quantum Dots Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Islamic Azad University
- Islamic Azad University, Sanadaj Branch