Sex‐Related Differences in Outcomes of Left Atrial Appendage Occlusion Device Placement

In patients with hospitalizations for LAAO device placement, we observed a higher risk of net adverse events and mortality in females following the procedure compared to males. Prospective trials are warranted to identify and stratify the at-risk population with extensive preprocedural evaluation and determine ways to mitigate the sex-related disparities in clinical outcomes following the LAAO procedure.

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Publication Details

Journal
Pacing and Clinical Electrophysiology
Published
2026-02-03
DOI
https://doi.org/10.1111/pace.70152
Primary Topic
Atrial Fibrillation Management and Outcomes
Type
article
Field-Weighted Citation Impact
0.00
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article

Sex‐Related Differences in Outcomes of Left Atrial Appendage Occlusion Device Placement

Paari Dominic, Zain Ul Abideen Asad, Bijeta Keisham, Thannon Alsaeed et al.
Pacing and Clinical Electrophysiology
Atrial Fibrillation Management and Outcomes
article

Sex‐Related Differences in Outcomes of Left Atrial Appendage Occlusion Device Placement

Paari Dominic, Zain Ul Abideen Asad, Bijeta Keisham, Thannon Alsaeed, Lalitsiri Atti, Pramod Kumar Ponna, Shafaqat Ali, Irisha Badu, Pratik K. Agrawal, Faryal Farooq, Tarek Helmy, Michael Sewell, Manoj Kumar, Vijaywant Brar, Sanchit Duhan, Abdul Rasheed Bahar
article en

Abstract

In patients with hospitalizations for LAAO device placement, we observed a higher risk of net adverse events and mortality in females following the procedure compared to males. Prospective trials are warranted to identify and stratify the at-risk population with extensive preprocedural evaluation and determine ways to mitigate the sex-related disparities in clinical outcomes following the LAAO procedure.

Pacing and Clinical Electrophysiology
Weifang Medical University (CN), University of Iowa (US), Carle Foundation Hospital (US), Sparrow Health System (US), Wayne State University (US), Allama Iqbal Medical College (PK), Louisiana State University in Shreveport (US), John H. Stroger, Jr. Hospital of Cook County (US), University of Oklahoma Medical Center (US), Onslow Memorial Hospital (US)
Good health and well-being
Openalex Percentile: Top 69%
Atrial Fibrillation Management and Outcomes
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