The effects of GLP-1 receptor agonists on metabolic inflammatory markers in patients with type 2 diabetes mellitus: a systematic review and meta-analysis
GLP-1 RAs exhibit a certain degree of anti-inflammatory effect in patients with T2DM, effectively reducing CRP and TNF-<i>α</i> levels. The anti-inflammatory efficacy appears to be influenced by both the type of drug used and the duration of treatment, with more pronounced effects observed for specific drug classes and with longer treatment periods. These findings provide further evidence supporting the use of GLP-1 RAs in the anti-inflammatory management of T2DM.
Authors
- Hezhang Yun (ORCID: https://orcid.org/0000-0003-1786-166X)
- Hao Wang (ORCID: https://orcid.org/0000-0001-6881-9977)
- Shenguang Li
- Fang Zhao
- Wenbo Su
Institutions
- Lanzhou University of Technology (CN)
- Southwest Medical University (CN)
- Huzhou Normal University (CN)
- Zhejiang DongFang Vocational and Technical College (CN)
- Macao Polytechnic University (MO)
- Lanzhou University (CN)
Publication Details
- Journal
- PeerJ
- Published
- 2026-02-03
- DOI
- https://doi.org/10.7717/peerj.20710
- Primary Topic
- Diabetes Treatment and Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00