Novel Cyclopentapyrrole Compounds as Orexin Receptor Agonists for Treating Sleep Disorders, namely, Narcolepsy and Hypersomnia

Provided herein are novel cyclopentapyrrole compounds as orexin receptor agonists, pharmaceutical compositions, use of such compounds in treating sleep disorders, namely, narcolepsy and hypersomnia, and processes for preparing such compounds.

Authors

Ram W. Sabnis (ORCID: https://orcid.org/0000-0001-7289-0581)

Publication Details

Journal: ACS Medicinal Chemistry Letters
Published: 2026-02-03
DOI: https://doi.org/10.1021/acsmedchemlett.6c00035
Primary Topic: Sleep and Wakefulness Research
Type: article
Field-Weighted Citation Impact: 0.00

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article

Novel Cyclopentapyrrole Compounds as Orexin Receptor Agonists for Treating Sleep Disorders, namely, Narcolepsy and Hypersomnia

Ram W. Sabnis

Feb 3, 2026

ACS Medicinal Chemistry Letters

Sleep and Wakefulness Research

article

Novel Cyclopentapyrrole Compounds as Orexin Receptor Agonists for Treating Sleep Disorders, namely, Narcolepsy and Hypersomnia

Ram W. Sabnis

February 3, 2026article en

Abstract

ACS Medicinal Chemistry LettersVol. 17(2)

Openalex Percentile: Top 69%

Sleep and Wakefulness Research

DOI Open Access PDF OpenAlex

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Novel Cyclopentapyrrole Compounds as Orexin Receptor Agonists for Treating Sleep Disorders, namely, Narcolepsy and Hypersomnia — Ram W. Sabnis · ACS Medicinal Chemistry Letters (2026) | TGRS Research Map | TGRS