Apparent brain death in snakebite: A reversible neurotoxic crisis

In the field of toxicology, snake bites are recognized as a significant cause capable of mimicking brain death. A neurotoxic snakebite can manifest with a wide range of symptoms, causing asymptomatic cases to more severe presentations. Common symptoms include ptosis and complete external and internal ophthalmoplegia, which indicate paralysis of the eye muscles. In severe cases, the bite can lead to complete respiratory failure, necessitating urgent medical intervention. Here, we present a patient with a neuro paralytic snake bite with conditions mimicking brain death. The patient achieved full neurological recovery following treatment with polyvalent snake antivenom and supportive care. This case underscores the importance of considering the neuroparalytic effects of snake bites when assessing patients, as it may lead to a false diagnosis of brain death. Intensivists should carefully evaluate these potential effects before deciding to withdraw ventilatory supp]ort or consider organ donation.

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Publication Details

Journal
Annals of the National Academy of Medical Sciences (India)
Published
2026-02-03
DOI
https://doi.org/10.25259/anams_148_2025
Primary Topic
Venomous Animal Envenomation and Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Apparent brain death in snakebite: A reversible neurotoxic crisis

Tidip Bordoloi, Amitesh Aggarwal, Alisha Khan, Pratima Goyal
Annals of the National Academy of Medical Sciences (India)
Venomous Animal Envenomation and Studies
article

Apparent brain death in snakebite: A reversible neurotoxic crisis

Tidip Bordoloi, Amitesh Aggarwal, Alisha Khan, Pratima Goyal
article en

Abstract

In the field of toxicology, snake bites are recognized as a significant cause capable of mimicking brain death. A neurotoxic snakebite can manifest with a wide range of symptoms, causing asymptomatic cases to more severe presentations. Common symptoms include ptosis and complete external and internal ophthalmoplegia, which indicate paralysis of the eye muscles. In severe cases, the bite can lead to complete respiratory failure, necessitating urgent medical intervention. Here, we present a patient with a neuro paralytic snake bite with conditions mimicking brain death. The patient achieved full neurological recovery following treatment with polyvalent snake antivenom and supportive care. This case underscores the importance of considering the neuroparalytic effects of snake bites when assessing patients, as it may lead to a false diagnosis of brain death. Intensivists should carefully evaluate these potential effects before deciding to withdraw ventilatory supp]ort or consider organ donation.

Annals of the National Academy of Medical Sciences (India)Vol. 0
University College of Medical Sciences (IN), Guru Teg Bahadur Hospital (IN)
Good health and well-being
Openalex Percentile: Top 65%
Venomous Animal Envenomation and Studies
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