Tissues Guide Dependence of Treg on the Transferrin Receptor

A loss of the transferrin receptor in Tregs causes severe autoimmunity and here we clarify how Tregs rely on this receptor for iron in specific tissues and disease settings including atopic dermatitis.

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Publication Details

Journal
bioRxiv (Cold Spring Harbor Laboratory)
Published
2026-02-03
DOI
https://doi.org/10.64898/2026.02.01.703140
Primary Topic
T-cell and B-cell Immunology
Type
article
Field-Weighted Citation Impact
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article

Tissues Guide Dependence of Treg on the Transferrin Receptor

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T-cell and B-cell Immunology
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Tissues Guide Dependence of Treg on the Transferrin Receptor

Denis A. Mogilenko, KayLee K. Steiner, Katherine N. Gibson‐Corley, Michelle Montoya, Yasmine T. Toudji, Anton Zhelonkin, Samantha St. Jean, Jeffrey C Rathmell, Ata Ur Rehman, Teresa Tamborra-Walton, Kelsey Voss
article en

Abstract

A loss of the transferrin receptor in Tregs causes severe autoimmunity and here we clarify how Tregs rely on this receptor for iron in specific tissues and disease settings including atopic dermatitis.

bioRxiv (Cold Spring Harbor Laboratory)
Vanderbilt University (US), University of Chicago (US), University of Virginia (US), Vanderbilt University Medical Center (US)
Good health and well-being
Openalex Percentile: Top 69%
T-cell and B-cell Immunology
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