Effectiveness and Predictors of House Dust Mite Subcutaneous Immunotherapy in Polysensitised Patients With Allergic Rhinitis: A Multicentre Retrospective Study
Single-allergen HDM AIT is effective in many polysensitised AR patients; however, its efficacy varies by coexisting allergen type and sIgE level. Patients co-sensitised to mould with high HDM and mould sIgE appeared to have poorer outcomes. These preliminary findings require confirmation in larger prospective studies to guide tailored AIT strategies.
Authors
- L S Li
- Shijie Zhuang
- Yongshi Yang
- Chuanhe Liu (ORCID: https://orcid.org/0000-0002-9504-8538)
- Yanmin Bao
- Li Sha
- Rongfei Zhu
- Zhouxian Pan
- Wenchao Guan
- Ruonan Chai
- Xiaoshang Lou
- Shengyang Yao
- Yin Wang
- Kai Guan
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Peking Union Medical College Hospital (CN)
- General Hospital of Shenyang Military Region (CN)
- Shenzhen Children's Hospital (CN)
- Tongji Hospital (CN)
- Children's Hospital of Capital Institute of Pediatrics (CN)
- Huazhong University of Science and Technology (CN)
Publication Details
- Journal
- Clinical & Experimental Allergy
- Published
- 2026-02-03
- DOI
- https://doi.org/10.1111/cea.70229
- Primary Topic
- Allergic Rhinitis and Sensitization
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Peking Union Medical College Hospital
- Peking Union Medical College