Adipokine CTRP12 Alleviates Experimental Colitis by Participating in Modulating Mesenteric M2 Macrophage Polarization in IL-10 KO Mice
These findings suggest adipokine CTRP12 could ameliorate Crohn's colitis by modulating polarization of mesenteric macrophages to M2 type, providing new target for Crohn's disease therapy.
Authors
- Yuanyuan Ge (ORCID: https://orcid.org/0000-0003-2842-3577)
- Miao Yu
- Qiang Leng
- Kang Ding
- Meng Li
- Tianyi Li
- Dongliang Guo
Institutions
- Nanjing University of Chinese Medicine (CN)
Publication Details
- Journal
- Digestive Diseases and Sciences
- Published
- 2026-02-04
- DOI
- https://doi.org/10.1007/s10620-026-09718-8
- Primary Topic
- Inflammatory Bowel Disease
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Government of Jiangsu Province