Overexpression of IL-8 augments the susceptibility to a hyperinflammatory phenotype in pediatric acute respiratory distress syndrome and correlates with adverse outcomes: a retrospective two-center study conducted in northwest China
IL-8 is overexpressed in children with ARDS, showing a prognostic potential particularly in combination with RAGE, Ang-2, ICAM-1 and SP-D in PARDS.
Authors
- Haitong Wu
- W D Wang
- Dan Yao (ORCID: https://orcid.org/0009-0004-2024-3066)
- Yuzhu Wang (ORCID: https://orcid.org/0009-0009-3416-316X)
- Zhangyan Guo
- Zhe Lv
- Yong Zhou
- Taining Zhang
- Le Ma
- Hua Zhang
- Yanqiang Du
- Li Liu
Institutions
- Gansu Provincial Maternal and Child Health Hospital (CN)
- First Affiliated Hospital of Xi'an Jiaotong University (CN)
- Second Affiliated Hospital of Xi'an Jiaotong University (CN)
- Xi’an Children’s Hospital (CN)
- Xi'an Jiaotong University (CN)
Publication Details
- Journal
- Frontiers in Pediatrics
- Published
- 2026-02-03
- DOI
- https://doi.org/10.3389/fped.2026.1626327
- Primary Topic
- Respiratory Support and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00