Lighting up PNETs: Creating Murine Models with a Novel Bioluminescent Cell Line
Orthotopic pancreatic implantation of dual-labeled STC-1 cells provides a biologically relevant and pragmatic preclinical platform that closely resembles human PNETs. This model offers valuable utility for investigating PNET biology and evaluating novel therapeutic strategies.
Authors
- Gena V Topper (ORCID: https://orcid.org/0009-0005-2234-3906)
- Young Ki Hong (ORCID: https://orcid.org/0000-0001-6634-1367)
- Matthew C. Moccia (ORCID: https://orcid.org/0009-0008-4607-3615)
- Ami Kalola
- Zena Saleh
- Rachel J. Nation (ORCID: https://orcid.org/0009-0007-0659-972X)
- Hannah Sofield
- Michael Wang
- Francis Spitz
- T. Hess
- Tao Gao
- Yahui Li
Institutions
- Cooper University Hospital (US)
- Coriell Institute For Medical Research (US)
- Cooper Medical School of Rowan University (US)
- Cooper University Health Care (US)
Publication Details
- Journal
- Annals of Surgical Oncology
- Published
- 2026-02-03
- DOI
- https://doi.org/10.1245/s10434-026-19089-z
- Citations
- 2
- Primary Topic
- Cancer Research and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 55.91