National Poison Center Trends in GLP-1 Receptor Agonist Exposures Following FDA Approval for Weight Loss

GLP-1 RA exposures rose sharply following semaglutide's weight-loss approval, accompanied by increased health care utilization despite generally mild clinical effects. Although multiple factors likely contributed to these trends, improved patient counseling and clearer poison center guidance may help reduce preventable therapeutic errors and unnecessary emergency evaluation.

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Publication Details

Journal
Journal of Medical Toxicology
Published
2026-02-03
DOI
https://doi.org/10.1007/s13181-026-01121-z
Primary Topic
Diabetes Treatment and Management
Type
article
Field-Weighted Citation Impact
0.00
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article

National Poison Center Trends in GLP-1 Receptor Agonist Exposures Following FDA Approval for Weight Loss

Shawn M. Varney, David Han, Jordan Miller, Robert J Miller
Journal of Medical Toxicology
Diabetes Treatment and Management
article

National Poison Center Trends in GLP-1 Receptor Agonist Exposures Following FDA Approval for Weight Loss

Shawn M. Varney, David Han, Jordan Miller, Robert J Miller
article en

Abstract

GLP-1 RA exposures rose sharply following semaglutide's weight-loss approval, accompanied by increased health care utilization despite generally mild clinical effects. Although multiple factors likely contributed to these trends, improved patient counseling and clearer poison center guidance may help reduce preventable therapeutic errors and unnecessary emergency evaluation.

Journal of Medical Toxicology
Texas A&M University – San Antonio (US), The University of Texas at San Antonio Health Science Center (US), Washington Poison Center (US)
Good health and well-being
Openalex Percentile: Top 71%
Diabetes Treatment and Management
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