Salivary Duct Carcinoma: Report of an Advanced Challenging Case Diagnosed by Ultrasound‐Guided Fine‐Needle Aspiration Biopsy
We report a rare case of salivary duct carcinoma (SDC) in a 67-year-old male who presented with a rapidly enlarging, ill-defined left upper neck mass, accompanied by both cervical and axillary lymphadenopathy. Initial punch biopsy of the neck mass suggested metastatic breast carcinoma. However, ultrasound-guided fine-needle aspiration (US-FNA) and comprehensive immunohistochemical analysis, in conjunction with radiologic findings, confirmed the diagnosis of SDC. This case highlights the diagnostic challenges of SDC and reinforces the pivotal role of US-FNA cytology in establishing a definitive diagnosis while minimizing invasive procedures.
Authors
- Prerna Khetan (ORCID: https://orcid.org/0000-0002-1963-1940)
- Maoxin Wu (ORCID: https://orcid.org/0000-0002-3082-2916)
Institutions
- Stony Brook School (US)
Publication Details
- Journal
- Diagnostic Cytopathology
- Published
- 2026-02-02
- DOI
- https://doi.org/10.1002/dc.70091
- Primary Topic
- Salivary Gland Tumors Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00