Treatment outcomes, safety, and characteristics of immune tolerance induction in patients with hemophilia B and inhibitors: a systematic review

The significant heterogeneity in outcome definitions and ITI protocols complicates the assessment of treatment efficacy. The high incidence of adverse events demands careful management strategies. Standardizing outcome definitions and ITI protocols is crucial to optimize patient management and improve outcomes.

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Publication Details

Journal
Research and Practice in Thrombosis and Haemostasis
Published
2026-02-01
DOI
https://doi.org/10.1016/j.rpth.2026.103379
Primary Topic
Hemophilia Treatment and Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Treatment outcomes, safety, and characteristics of immune tolerance induction in patients with hemophilia B and inhibitors: a systematic review

Shaoyu Yin, Zeping Zhou, Hui Bi, Jiahong Wu et al.
Research and Practice in Thrombosis and Haemostasis
Hemophilia Treatment and Research
article

Treatment outcomes, safety, and characteristics of immune tolerance induction in patients with hemophilia B and inhibitors: a systematic review

Shaoyu Yin, Zeping Zhou, Hui Bi, Jiahong Wu, Hongli Mu, Yuexing Peng, Rong Li, Haoran Lu, Wen Yang
article en

Abstract

The significant heterogeneity in outcome definitions and ITI protocols complicates the assessment of treatment efficacy. The high incidence of adverse events demands careful management strategies. Standardizing outcome definitions and ITI protocols is crucial to optimize patient management and improve outcomes.

Research and Practice in Thrombosis and HaemostasisVol. 10(2)
Kunming Medical University (CN)
Good health and well-being
Openalex Percentile: Top 71%
Hemophilia Treatment and Research
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Treatment outcomes, safety, and characteristics of immune tolerance induction in patients with hemophilia B and inhibitors: a systematic review — Shaoyu Yin, Zeping Zhou, et al. · Research and Practice in Thrombosis and Haemostasis (2026) | TGRS Research Map | TGRS