18F-DOPA-PET and Advanced MRI Improve Treatment Response Assessment in <i>IDH1/2</i> -Mutant Gliomas Treated with IDH Inhibitors

These results highlight the potential of ¹⁸F-DOPA-PET and advanced MRI sequences as valuable complements to standard RANO 2.0 MRI evaluations for assessing treatment response in glioma patients undergoing IDHi therapy.

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Publication Details

Journal
Clinical Cancer Research
Published
2026-02-02
DOI
https://doi.org/10.1158/1078-0432.ccr-25-0279
Primary Topic
Glioma Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
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article

18F-DOPA-PET and Advanced MRI Improve Treatment Response Assessment in IDH1/2 -Mutant Gliomas Treated with IDH Inhibitors

K Hoang-Xuan, Alice Laurenge, M. Touat, M. Sanson et al.
Clinical Cancer Research
Glioma Diagnosis and Treatment
article

18F-DOPA-PET and Advanced MRI Improve Treatment Response Assessment in IDH1/2 -Mutant Gliomas Treated with IDH Inhibitors

K Hoang-Xuan, Alice Laurenge, M. Touat, M. Sanson, Francesca Branzoli, Lucia Nichelli, Ángel Escamilla-Ramírez, Julien Savatovsky, Julian Jacob, Louisa Drouiche, Ahmed Idbaih, Diego Prost, Laura Rozenblum, Bertrand Mathon, Caroline Dehais, Franck Bielle
article en

Abstract

These results highlight the potential of ¹⁸F-DOPA-PET and advanced MRI sequences as valuable complements to standard RANO 2.0 MRI evaluations for assessing treatment response in glioma patients undergoing IDHi therapy.

Clinical Cancer Research
Brigham and Women's Hospital (US), Centre National de la Recherche Scientifique (FR), Inserm (FR), Sorbonne Université (FR), Assistance Publique – Hôpitaux de Paris (FR), Laboratoire d’Imagerie Biomédicale (FR), Pitié-Salpêtrière Hospital (FR), Ramsay Santé Hôpital privé des Peupliers (FR), Fondation de Rothschild (FR), Institut de Psychiatrie et Neurosciences de Paris (FR), Hôpital Charles-Foix (FR)
Good health and well-being
Openalex Percentile: Top 69%
Glioma Diagnosis and Treatment
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