Deep characterization of refractory epilepsy due to mild malformation of cortical development with oligodendroglial hyperplasia ( <scp>MOGHE</scp> ) and insights into the role of invasive monitoring
Our results underscore the pivotal role of SEEG in enhancing surgical outcomes in patients with drug-resistant epilepsy due to MOGHE. SEEG proved particularly beneficial in defining resection margins, especially in cases where non-invasive data were discordant, scalp EEG patterns were generalized or poorly localized, and imaging findings were nonspecific, diffuse, or normal, making lesion identification challenging.
Authors
- Demitre Serletis (ORCID: https://orcid.org/0000-0002-8037-9705)
- Juan Bulacio (ORCID: https://orcid.org/0000-0002-2547-518X)
- Balu Krishnan
- Jean Khoury
- Ingmar Blümcke
- William Bingaman
- Imad Najm
- Robyn M. Busch
Institutions
- Cleveland Clinic (US)
- Universitätsklinikum Erlangen (DE)
Publication Details
- Journal
- Epilepsia
- Published
- 2026-02-02
- DOI
- https://doi.org/10.1002/epi.70118
- Primary Topic
- Epilepsy research and treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00