Early detection of type 2 diabetes mellitus‐associated cognitive dysfunction: The potential of amide proton transfer‐weighted imaging
APTw imaging suggested a spatially evolving pattern of hippocampal damage in T2DM, where the left body may show early alterations, with the left head potentially becoming more implicated upon MCI onset. These findings provide preliminary evidence supporting the potential of APTw as an early, non-invasive biomarker for tracking neuropathological progression in DACD.
Authors
- Thomas C. Booth (ORCID: https://orcid.org/0000-0003-0984-3998)
- Ying Yang (ORCID: https://orcid.org/0009-0004-6879-0982)
- Yan Zhang (ORCID: https://orcid.org/0000-0002-9707-2953)
- Jing Fang
- Hong‐yan Dai
- Ju‐wei Shao
Institutions
- King's College London (GB)
- Yunnan University (CN)
- Kunming Medical University (CN)
- Second People's Hospital of Yunnan Province (CN)
Publication Details
- Journal
- Diabetes Obesity and Metabolism
- Published
- 2026-02-02
- DOI
- https://doi.org/10.1111/dom.70468
- Primary Topic
- Lanthanide and Transition Metal Complexes
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Kunming Medical University
- Yunnan University
- Medical Research Council
- Engineering and Physical Sciences Research Council
- Centre For Medical Engineering, King’s College London