Hormone Receptor Status as a Predictive Factor for Pathological Complete Response to Neoadjuvant Dual HER2 Blockade in Patients with HER2-Positive Breast Cancer: A Multicenter Retrospective Study
HR status is a strong and independent predictor of pCR in HER2-positive breast cancer patients receiving neoadjuvant dual blockade. Patients with HR- disease derive the most benefit from this regimen, highlighting the need for tailored therapeutic strategies to improve outcomes for the HR+ subgroup.
Authors
- Xuqun Huang
- Qun Liang
- Shaoping Liu
- Guojun Liu
Institutions
- Huangshi Central Hospital (CN)
Publication Details
- Journal
- Breast Care
- Published
- 2026-02-02
- DOI
- https://doi.org/10.1159/000550380
- Primary Topic
- HER2/EGFR in Cancer Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00