Effective treatment of acute graft-versus-host disease following liver transplantation using an integrated regimen centered on antithymocyte globulin: a single-center experience

The diagnosis of aGVHD after LT requires integrating clinical manifestations, rash pathology, and chimerism detection. In this small series, ATG-based therapy was associated with favorable outcomes compared with a historical cohort receiving conventional therapy, suggesting that it may be a promising strategy warranting further evaluation in large-scale clinical studies.

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Publication Details

Journal
Frontiers in Immunology
Published
2026-02-03
DOI
https://doi.org/10.3389/fimmu.2026.1696936
Primary Topic
Hematopoietic Stem Cell Transplantation
Type
article
Field-Weighted Citation Impact
0.00

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article

Effective treatment of acute graft-versus-host disease following liver transplantation using an integrated regimen centered on antithymocyte globulin: a single-center experience

Fang Liu, X Xiao, Honghai Wang, Li Zhang et al.
Frontiers in Immunology
Hematopoietic Stem Cell Transplantation
article

Effective treatment of acute graft-versus-host disease following liver transplantation using an integrated regimen centered on antithymocyte globulin: a single-center experience

Fang Liu, X Xiao, Honghai Wang, Li Zhang, Ababakri Abdisamat, Qiming Zheng, Wentao Jiang
article en

Abstract

The diagnosis of aGVHD after LT requires integrating clinical manifestations, rash pathology, and chimerism detection. In this small series, ATG-based therapy was associated with favorable outcomes compared with a historical cohort receiving conventional therapy, suggesting that it may be a promising strategy warranting further evaluation in large-scale clinical studies.

Frontiers in ImmunologyVol. 17
Nankai University (CN), Tianjin First Center Hospital (CN), Tianjin Medical University General Hospital (CN), Tianjin Medical University (CN)
Nankai University
Good health and well-being
Openalex Percentile: Top 72%
Hematopoietic Stem Cell Transplantation
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