Clinical Efficacy of Levocarnitine-Alprostadil Combination Therapy on Indicators of Renal Function, Oxidant-Antioxidant Balance, and Systemic Inflammation in Patients with End-Stage Diabetic Nephropathy

In ESDN patients, the combination of Levocarnitine and Alprostadil demonstrates superior cumulative treatment effectiveness over Alprostadil monotherapy in improving renal function, reducing oxidative stress, and attenuating inflammation, without increasing the incidence of adverse reactions.

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Publication Details

Journal
Therapeutics and Clinical Risk Management
Published
2026-02-01
DOI
https://doi.org/10.2147/tcrm.s553649
Primary Topic
Chronic Kidney Disease and Diabetes
Type
article
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article

Clinical Efficacy of Levocarnitine-Alprostadil Combination Therapy on Indicators of Renal Function, Oxidant-Antioxidant Balance, and Systemic Inflammation in Patients with End-Stage Diabetic Nephropathy

Shuai Fu, Yonglong Min, Dongdong Mao, Can Tu et al.
Therapeutics and Clinical Risk Management
Chronic Kidney Disease and Diabetes
article

Clinical Efficacy of Levocarnitine-Alprostadil Combination Therapy on Indicators of Renal Function, Oxidant-Antioxidant Balance, and Systemic Inflammation in Patients with End-Stage Diabetic Nephropathy

Shuai Fu, Yonglong Min, Dongdong Mao, Can Tu, Li Cheng, Sheng Wan, Quan Wang, Fei Xiong
article en

Abstract

In ESDN patients, the combination of Levocarnitine and Alprostadil demonstrates superior cumulative treatment effectiveness over Alprostadil monotherapy in improving renal function, reducing oxidative stress, and attenuating inflammation, without increasing the incidence of adverse reactions.

Therapeutics and Clinical Risk ManagementVol. Volume 22
Wuhan No.1 Hospital (CN), Wuhan No.9 Hospital (CN)
Good health and well-being
Openalex Percentile: Top 73%
Chronic Kidney Disease and Diabetes
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