Loss of IL1RA promotes prostate cancer growth and metastasis by activating Akt signaling pathway
This study revealed that IL1RA low expression is associated with PCa progression. Our finding has great clinical and translational significance. The potential clinical application of IL1RA as a therapeutic target for PCa requires further investigation.
Authors
- Mingquan Chen (ORCID: https://orcid.org/0000-0003-0911-9836)
- Taoze Ji
- Cheng Zhang
- Junjie Yu
- Kai Zhao
Institutions
- Nanjing University of Chinese Medicine (CN)
- Northern Jiangsu People's Hospital (CN)
- Guangdong Academy of Medical Sciences (CN)
- Jiangsu Province Hospital (CN)
- Guangdong Provincial People's Hospital (CN)
- Southern Medical University (CN)
Publication Details
- Journal
- PLoS ONE
- Published
- 2026-02-02
- DOI
- https://doi.org/10.1371/journal.pone.0339611
- Primary Topic
- Immune Response and Inflammation
- Type
- article
- Field-Weighted Citation Impact
- 0.00