From genetic risk to early detection - clinical outcomes of a person-centered screening program for women with a high genetic risk of breast cancer

The PGO's coordinated, person-centered approach to high genetic risk management was likely associated with earlier-stage BC detection in women with the <i>BRCA</i> PV and women at high risk without <i>BRCA PV</i>. These findings both underscore the enhanced value of person-centered surveillance programs that integrate genetic risk assessment and long-term clinical follow-up, and pave the way for further research in this area.