The role of cartridge-based nucleic acid amplification test (CBNAAT) in early diagnosis of extra pulmonary tuberculosis – a case report

Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis. It primarily affects the lungs, leading to Hemoptysis, which is the most frequent manifestation. When organs other than the lungs, pleura, such as lymph nodes, abdomen, reproductive organs (testicles, ovaries), skin, meninges, bones, and joints are affected, it is called extrapulmonary tuberculosis (EPTB). Recently, the Cartridge-based Nucleic Acid Amplification Test (CBNAAT) has shown higher sensitivity and specificity than other diagnostic tests in individuals with active and latent tuberculosis infection. This case highlights the importance of early and rapid diagnosis of tuberculous cervical lymphadenitis (scrofula) in a 38-year-old female using a cartridge-based nucleic acid amplification test (CBNAAT) and its treatment with antitubercular drugs, followed up 2 months after antitubercular drug treatment.

Authors

Publication Details

Journal
Springer Link (Chiba Institute of Technology)
Published
2025-08-28
DOI
https://doi.org/10.1051/mbcb/2025025/pdf
Primary Topic
Lymphadenopathy Diagnosis and Analysis
Type
article
Field-Weighted Citation Impact
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article

The role of cartridge-based nucleic acid amplification test (CBNAAT) in early diagnosis of extra pulmonary tuberculosis – a case report

Sabitha Gokulraj, R Thiruneervannan, Ramachandra Reddy Gowda Venkatesha, Saramma Mathew Fenn et al.
Springer Link (Chiba Institute of Technology)
Lymphadenopathy Diagnosis and Analysis
article

The role of cartridge-based nucleic acid amplification test (CBNAAT) in early diagnosis of extra pulmonary tuberculosis – a case report

Sabitha Gokulraj, R Thiruneervannan, Ramachandra Reddy Gowda Venkatesha, Saramma Mathew Fenn, Karthik Rajaram Mohan, Vinitha Ganesh
article en

Abstract

Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis. It primarily affects the lungs, leading to Hemoptysis, which is the most frequent manifestation. When organs other than the lungs, pleura, such as lymph nodes, abdomen, reproductive organs (testicles, ovaries), skin, meninges, bones, and joints are affected, it is called extrapulmonary tuberculosis (EPTB). Recently, the Cartridge-based Nucleic Acid Amplification Test (CBNAAT) has shown higher sensitivity and specificity than other diagnostic tests in individuals with active and latent tuberculosis infection. This case highlights the importance of early and rapid diagnosis of tuberculous cervical lymphadenitis (scrofula) in a 38-year-old female using a cartridge-based nucleic acid amplification test (CBNAAT) and its treatment with antitubercular drugs, followed up 2 months after antitubercular drug treatment.

Springer Link (Chiba Institute of Technology)
Good health and well-being
Openalex Percentile: Top 23%
Lymphadenopathy Diagnosis and Analysis
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The role of cartridge-based nucleic acid amplification test (CBNAAT) in early diagnosis of extra pulmonary tuberculosis – a case report — Sabitha Gokulraj, R Thiruneervannan, et al. · Springer Link (Chiba Institute of Technology) (2025) | TGRS Research Map | TGRS