Nitrogen Species Modulate Macrophage ER Stress to Preserve Alveolar Bone: A Translational Adjunct for Periodontal Care

These preclinical data support PBNI as a chairside host-modulatory adjunct to non-surgical periodontal therapy by restoring immune homeostasis and creating a bone-forming microenvironment. The approach is conceptually compatible with short, operator-delivered applications and standard infection-control workflows.

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Publication Details

Journal
International Dental Journal
Published
2026-02-03
DOI
https://doi.org/10.1016/j.identj.2025.109400
Primary Topic
Oral microbiology and periodontitis research
Type
article
Field-Weighted Citation Impact
0.00
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article

Nitrogen Species Modulate Macrophage ER Stress to Preserve Alveolar Bone: A Translational Adjunct for Periodontal Care

Ollie Yiru Yu, Laidi Wu, Xinpei Lu, Yingguang Cao et al.
International Dental Journal
Oral microbiology and periodontitis research
article

Nitrogen Species Modulate Macrophage ER Stress to Preserve Alveolar Bone: A Translational Adjunct for Periodontal Care

Ollie Yiru Yu, Laidi Wu, Xinpei Lu, Yingguang Cao, Ke Song, Ming Luo, Zhixin Liu
article en

Abstract

These preclinical data support PBNI as a chairside host-modulatory adjunct to non-surgical periodontal therapy by restoring immune homeostasis and creating a bone-forming microenvironment. The approach is conceptually compatible with short, operator-delivered applications and standard infection-control workflows.

International Dental JournalVol. 76(2)
Education University of Hong Kong (HK), Huazhong University of Science and Technology (CN), University of Hong Kong (HK)
Zero hunger
Openalex Percentile: Top 69%
Oral microbiology and periodontitis research
DOIOpen Access PDFOpenAlex
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Nitrogen Species Modulate Macrophage ER Stress to Preserve Alveolar Bone: A Translational Adjunct for Periodontal Care — Ollie Yiru Yu, Laidi Wu, et al. · International Dental Journal (2026) | TGRS Research Map | TGRS