Synergistic immune interactions between T cells and natural killer cells in allogeneic haematopoietic stem cell transplantation for acute myeloid leukaemia: current status and future directions
The dynamic interplay between T cells and NK cells plays a pivotal role in allo-HSCT for AML. This review systematically integrates the cooperative functions of T cells and NK cells within the allo-HSCT immune landscape, offering new perspectives for advancing post-transplant immunotherapy. A deeper understanding of these mechanisms is expected to provide a theoretical foundation for optimizing post-transplant immune interventions in AML patients and for developing more precise therapeutic strategies.
Authors
- Hanxue Zheng
- Liansheng Zhang (ORCID: https://orcid.org/0009-0005-0402-6990)
- Lijuan Li (ORCID: https://orcid.org/0000-0001-9986-7832)
- Pingling Yin
- Nan Wang (ORCID: https://orcid.org/0000-0002-0983-3389)
- Zhengdong Hao
Institutions
- Gansu Provincial Cancer Hospital Gansu Provincial Academic Instiute for Medical Research (CN)
- Lanzhou University Second Hospital (CN)
- Pingliang People's Hospital (CN)
- Lanzhou University (CN)
Publication Details
- Journal
- Annals of Medicine
- Published
- 2026-02-02
- DOI
- https://doi.org/10.1080/07853890.2025.2601404
- Primary Topic
- Immune Cell Function and Interaction
- Type
- article
- Field-Weighted Citation Impact
- 0.00