Synergistic immune interactions between T cells and natural killer cells in allogeneic haematopoietic stem cell transplantation for acute myeloid leukaemia: current status and future directions

The dynamic interplay between T cells and NK cells plays a pivotal role in allo-HSCT for AML. This review systematically integrates the cooperative functions of T cells and NK cells within the allo-HSCT immune landscape, offering new perspectives for advancing post-transplant immunotherapy. A deeper understanding of these mechanisms is expected to provide a theoretical foundation for optimizing post-transplant immune interventions in AML patients and for developing more precise therapeutic strategies.

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Publication Details

Journal
Annals of Medicine
Published
2026-02-02
DOI
https://doi.org/10.1080/07853890.2025.2601404
Primary Topic
Immune Cell Function and Interaction
Type
article
Field-Weighted Citation Impact
0.00
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article

Synergistic immune interactions between T cells and natural killer cells in allogeneic haematopoietic stem cell transplantation for acute myeloid leukaemia: current status and future directions

Hanxue Zheng, Liansheng Zhang, Lijuan Li, Pingling Yin et al.
Annals of Medicine
Immune Cell Function and Interaction
article

Synergistic immune interactions between T cells and natural killer cells in allogeneic haematopoietic stem cell transplantation for acute myeloid leukaemia: current status and future directions

Hanxue Zheng, Liansheng Zhang, Lijuan Li, Pingling Yin, Nan Wang, Zhengdong Hao
article en

Abstract

The dynamic interplay between T cells and NK cells plays a pivotal role in allo-HSCT for AML. This review systematically integrates the cooperative functions of T cells and NK cells within the allo-HSCT immune landscape, offering new perspectives for advancing post-transplant immunotherapy. A deeper understanding of these mechanisms is expected to provide a theoretical foundation for optimizing post-transplant immune interventions in AML patients and for developing more precise therapeutic strategies.

Annals of MedicineVol. 58(1)
Gansu Provincial Cancer Hospital Gansu Provincial Academic Instiute for Medical Research (CN), Lanzhou University Second Hospital (CN), Pingliang People's Hospital (CN), Lanzhou University (CN)
Openalex Percentile: Top 69%
Immune Cell Function and Interaction
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