Population genetics of Plasmodium vivax with transmission decline and rebound in two endemic areas of Papua New Guinea

The earlier implementation of LLIN in East Sepik, smaller rebound, heterogeneity in transmission and relative isolation, compared to Madang may have contributed to these differing patterns. The results demonstrate that long term sustained control efforts are essential to make a lasting impact on the <i>P. vivax</i> population, and that SNP barcodes can provide valuable insights into parasite transmission dynamics as a result of control efforts.

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Publication Details

Journal
Frontiers in Genetics
Published
2026-02-03
DOI
https://doi.org/10.3389/fgene.2025.1621920
Primary Topic
Malaria Research and Control
Type
article
Field-Weighted Citation Impact
0.00

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article

Population genetics of Plasmodium vivax with transmission decline and rebound in two endemic areas of Papua New Guinea

Zahra Razook, Dulcie Lautu‐Gumal, Johanna Helena Kattenberg, J. W. Kazura et al.
Frontiers in Genetics
Malaria Research and Control
article

Population genetics of Plasmodium vivax with transmission decline and rebound in two endemic areas of Papua New Guinea

Zahra Razook, Dulcie Lautu‐Gumal, Johanna Helena Kattenberg, J. W. Kazura, Elma Nate, Cristian Koepfli, Somya Mehra, Ivo Mueller, Stuart Lee, Moses Laman, Leanne J. Robinson, Alyssa E. Barry, Maria Ome-Kaius
article en

Abstract

The earlier implementation of LLIN in East Sepik, smaller rebound, heterogeneity in transmission and relative isolation, compared to Madang may have contributed to these differing patterns. The results demonstrate that long term sustained control efforts are essential to make a lasting impact on the <i>P. vivax</i> population, and that SNP barcodes can provide valuable insights into parasite transmission dynamics as a result of control efforts.

Frontiers in GeneticsVol. 16
Burnet Institute (AU), Deakin University (AU), Institut Pasteur (FR), The University of Melbourne (AU), Walter and Eliza Hall Institute of Medical Research (AU), Monash University (AU), Case Western Reserve University (US), Papua New Guinea Institute of Medical Research (PG)
Australian Government, Medical Research Council, National Health and Medical Research Council
Good health and well-being
Openalex Percentile: Top 71%
Malaria Research and Control
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