Missing assent: a global systematic review of ethical practices in HIV research with men who have sex with men (MSM) under 18

This review highlights inconsistencies in how informed assent is addressed in HIV research involving MSM minors. Only one in five studies described ethically appropriate, youth-tailored processes. Limited use of waivers and adapted assent procedures points to ongoing gaps in aligning research with ethical standards. Future studies should adopt clearer, age-appropriate consent practices, ensure transparent reporting, and strengthen researcher training in ethics involving vulnerable minors.

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Publication Details

Journal
BMC Medical Ethics
Published
2026-02-03
DOI
https://doi.org/10.1186/s12910-026-01378-7
Primary Topic
HIV/AIDS Research and Interventions
Type
article
Field-Weighted Citation Impact
0.00
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article

Missing assent: a global systematic review of ethical practices in HIV research with men who have sex with men (MSM) under 18

Worawalan Waratworawan, Thomas E. Guadamuz, T Charles Witzel, Sin How Lim
BMC Medical Ethics
HIV/AIDS Research and Interventions
article

Missing assent: a global systematic review of ethical practices in HIV research with men who have sex with men (MSM) under 18

Worawalan Waratworawan, Thomas E. Guadamuz, T Charles Witzel, Sin How Lim
article en

Abstract

This review highlights inconsistencies in how informed assent is addressed in HIV research involving MSM minors. Only one in five studies described ethically appropriate, youth-tailored processes. Limited use of waivers and adapted assent procedures points to ongoing gaps in aligning research with ethical standards. Future studies should adopt clearer, age-appropriate consent practices, ensure transparent reporting, and strengthen researcher training in ethics involving vulnerable minors.

BMC Medical EthicsVol. 27(1)
Mahidol University (TH), University of Malaya (MY), University College London (GB)
No poverty
Openalex Percentile: Top 67%
HIV/AIDS Research and Interventions
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