Effects of Xinghanxiang Nasal Inhalation Therapy on Obstructive Sleep Apnea–Hypopnea Syndrome and Upper Airway Inflammation

Xinghanxiang nasal inhalation therapy significantly improves clinical symptoms in patients with OSAHS. Combined therapy with CPAP further improves ESS and AHI, with no significant adverse effects, supporting the need for large-scale studies and broader clinical application. Furthermore, Xinghanxiang nasal inhalation therapy significantly reduces CRP and IL-6 levels in nasal lavage fluid, suggesting that its mechanism of action may be related to alleviation of upper airway inflammation.

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Publication Details

Journal
Journal of Craniofacial Surgery
Published
2026-02-02
DOI
https://doi.org/10.1097/scs.0000000000012498
Primary Topic
Obstructive Sleep Apnea Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Effects of Xinghanxiang Nasal Inhalation Therapy on Obstructive Sleep Apnea–Hypopnea Syndrome and Upper Airway Inflammation

Zhongda Liu, Xiaojun Yang, Xia Liu, Quan Li et al.
Journal of Craniofacial Surgery
Obstructive Sleep Apnea Research
article

Effects of Xinghanxiang Nasal Inhalation Therapy on Obstructive Sleep Apnea–Hypopnea Syndrome and Upper Airway Inflammation

Zhongda Liu, Xiaojun Yang, Xia Liu, Quan Li, Chuan-Feng Liu, Xin-Li Chen, Tao Sun
article en

Abstract

Xinghanxiang nasal inhalation therapy significantly improves clinical symptoms in patients with OSAHS. Combined therapy with CPAP further improves ESS and AHI, with no significant adverse effects, supporting the need for large-scale studies and broader clinical application. Furthermore, Xinghanxiang nasal inhalation therapy significantly reduces CRP and IL-6 levels in nasal lavage fluid, suggesting that its mechanism of action may be related to alleviation of upper airway inflammation.

Journal of Craniofacial Surgery
Zhejiang Chinese Medical University (CN), Guizhou University (CN), Lishui University (CN), Lishui Central Hospital (CN)
Openalex Percentile: Top 68%
Obstructive Sleep Apnea Research
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