Importance of Recombinant Tissue Plasminogen Activator (rt-PA) thrombolysis in hyperacute stroke patients with aphasia – A case report

Background: Thrombolysis in an acute stroke has been shown to have a good outcome measure in an eligible candidate. However, the benefits and effectiveness of it in acute minor stroke are still not well established. Case description: We describe a case of 35-year-old male who was presented with isolated aphasia with the total National Institutes of Health Stroke Scale of 3 out of 42. Magnetic Resonance Imaging of the brain showed a focal left middle cerebral artery territory infarction secondary to distal vessel occlusion at M4 segment distally on Diffusion-Weighted Imaging sequence which was mismatched on Fluid-Attenuated Inversion Recovery sequence. Recombined tissue plasminogen activator was administrated intravenously without any complication. The patient's condition improved gradually with positive outcome measures. Conclusion: Intravenous r-TPA can be a beneficial treatment for a subset of patients with minor stroke.